Chelsea Handler Donates $100,000 to Red Cross for Hurricane Sandy Relief

Comedian Chelsea Handler arrives at amfAR's Inspiration Gala at Milk Studios on October 11, 2012 in Los Angeles, California. Credit: Jeff Vespa/Getty Images for amfAR

Chelsea Handler is giving back in a big way.

When John C. Reilly stopped by the comedienne's E! talk show, Chelsea Lately, on Oct. 31, the Wreck-It Ralph star asked audience members and television viewers to donate $10 to the Red Cross' relief efforts for Hurricane Sandy by texting REDCROSS to 90999.

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"People are going to be dealing with it for a long time," Reilly, 47, explained.

"I'm gonna do it right now. Go ahead, keep talking," the actor told Handler, 37. "Ask whatever you want."

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Inspired by Reilly's generosity, Handler -- a New Jersey native -- pledged to donate $100,000 to the ! Red Cross in the actor's name.

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Other celebrities who have asked fans to donate to the Red Cross' relief efforts include LL Cool J, Jennifer Lopez, Cindy Crawford and Denise Richards. On Friday, Nov. 2, at 8 p.m. EST, musicians including Christina Aguilera and Jon Bon Jovi will perform during a one-hour telethon, Hurricane Sandy: Coming Together, on several NBCUniversal networks.